Vardenafil vs Other Medications for Early Ejaculation

Other > vardenafil premature ejaculation


Your penis absorbs the anesthetic cream or spray in about 10 to 30 minutes.

From Mayo Clinic to your inbox

This could range from history of sexual abuse to hostile feelings about your partner. These could include feeling guilty or overwhelmed. This includes body image issues or lack of confidence. A hormonal problem involving oxytocin levels, which has a role in sexual function — other hormone levels that play a role in sexual function include luteinizing hormone (LH), prolactin and thyroid stimulating hormone (TSH) Low serotonin or dopamine levels, which are chemicals in your brain that are involved in sexual desire and excitement A penis that’s extra sensitive to stimulation It’s worth noting that premature ejaculation isn’t typically due to an underlying penile disorder, disease, infection or problem with your reproductive organs. Most of the time, everything is working as it should and the problem comes from stress, nervousness and anxiety.

SSRI drug interactions

The only symptom of premature ejaculation is ejaculating too soon. Premature ejaculation can have a significant effect on your relationship with your partner, making the complications psychological rather than physically harmful. You may feel embarrassed or that you can’t satisfy your partner. This can lead to issues with intimacy and impact your relationship as a whole. It’s common for people with PE sex power tablet to experience depression and frustration.

Off-Label Uses

For this reason, it’s important to seek help for PE. It’s a common condition that frustrates many people. Your healthcare provider can help determine the best treatment for you depending on the cause of your premature ejaculation. If you have frequent premature ejaculations or if premature ejaculation is causing you anxiety or depression and affecting your relationship, make an appointment to see a urologist. Your urologist will begin an exam by asking about your sexual experiences. It causes you to experience less sensitivity in your penis.

Product Dosage Quantity + Bonus Price
Apcalis SX Oral Jelly20mg10 Sachets58.75€ 55.95€
Kamagra Oral Jelly100 mg220 + 18 Sachets662.24€ 630.70€
Cialis Black80mg270 + 10 Pills502.88€ 478.93€
Cialis Black80mg180 + 10 Pills356.64€ 339.66€
Viagra Generic100mg360 + 10 Pills330.21€ 314.49€
Viagra Generic200mg20 Pills61.69€ 58.75€
Cialis Generic10mg120 + 6 Pills178.49€ 169.99€
Cialis Soft Tabs20mg30 + 4 Pills87.43€ 83.27€
Levitra Generic20mg90 + 8 Pills180.78€ 172.17€
Kamagra Effervescent Tablets100 mg63 + 7 Pills171.99€ 163.80€
Cialis Super Active20mg180 + 20 Pills521.59€ 496.75€
Kamagra Polo100 mg84 + 4 Pills244.49€ 232.85€

It’s important to wash your penis before sex to prevent numbness to your partner’s genitals.

How well do pills work against ejaculation too fast?

How long have you had this problem? Does premature ejaculation happen at every sexual encounter? Does premature ejaculation occur when you masturbate? Do you have trouble maintaining an erection? While the questions are personal, it’s important that you answer your urologist honestly so they can best diagnose the source of your problem.

Paroxetine hydrochloride

Your urologist will also ask about any other medical conditions you may have and any medications, including over-the-counter medications, supplements and herbal products you’re taking. They’ll also ask you about any alcohol and drug use. Lab tests are usually not needed unless your healthcare provider suspects that an underlying health condition is contributing to the problem. There are many different treatment options for premature ejaculation depending on the cause. These include behavioral therapy, counseling and medications.

Information to gather in advance

Most causes of premature ejaculation are usually treated first with behavioral therapy and/or counseling to help with emotional concerns, performance anxiety or stressors that may be contributing. You can try more than one treatment approach at the same time, and in fact, combinational therapy may be more effective than any one treatment alone. Behavioral therapy involves trying different practical methods to delay your orgasm. The goal is to teach you how to control your body and your feelings. With this technique, you or your partner stimulates your penis close to the point of orgasm, then stops the stimulation for about 30 seconds until you regain control of your response. Erectile dysfunction medications, which include sildenafil (Viagra®), tadalafil (Cialis®), vardenafil (Levitra®) and avanafil (Stendra®), may help treat premature ejaculation, particularly in people with underlying erectile dysfunction.

Medication Summary

Premature ejaculation can be a frustrating experience for both you and your sexual partner and make your sex lives less enjoyable. PE can be lifelong, meaning you’ve had it since your first sexual experience. It can also be acquired, which means you’ve had sex previously where PE wasn’t an issue. Many healthcare providers would define premature ejaculation as ejaculating within one minute of beginning intercourse. The exact timing for premature ejaculation varies and only your healthcare provider can make a diagnosis.

Tramadol (Ultram, Rybix ODT, ConZip, Ryzolt)

Most healthcare organizations consider ejaculation “premature” if it: Occurs sooner than you or your partner desires. Causes distress to one or both partners. Happens during all or almost all sexual activity. Has been occurring for longer than six months to one year. Between 30% and 40% of people experience premature ejaculation at some point in their lives.

Efficacy of fluvoxamine in treatment of PE

It’s the most common type of sexual dysfunction in people with a penis, with about 1 in 5 people between the ages of 18 and 59 reporting premature ejaculation. Anxiety/psychological factors are most often the cause of premature ejaculation. Extra sensitive penile skin is also a common cause. It could come from the nervousness of being with a new partner, the anxiousness of having sex again after a long period of abstinence, being overly excited or other reasons. Stress could be coming from work, other relationships, life changes or other events in your life. In certain cases, your provider may prescribe tramadol, an opiate medication. While alternative therapies also exist for PE treatment, there isn’t enough evidence to prove they’re effective.

Vardenafil (Generic Levitra®) FAQs

The pharmacological effect of citalopram residues in the (S)-(+)-enantiomer. Efficacy and tolerability of escitalopram in treatment of major depressive disorder with anxiety symptoms: a 24-week, open-label, prospective study in Chinese population. Clinical pharmacokinetics of selective serotonin reuptake inhibitors. De Jonghe F, Swinkels J, Tuyaman Qua H. Randomized double-blind study of fluoxamine and maprotiline in treatment of depression.

Paroxetine (Paxil, Pexeva)

Efficacy of dapoxetine in the treatment of premature ejaculation. Premature ejaculation occurs when you ejaculate (cum) earlier than you or your partner would like during sex. It’s a common problem, affecting 30% to 40% of people with a penis. Causes include physical problems, chemical imbalances and emotional/psychological factors. Treatments include learning techniques to delay ejaculation, counseling and medications.

Mechanism of action and efficacy of clomipramine in the treatment of PE

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Premature ejaculation (PE) is a type of sexual dysfunction that occurs when a person has an orgasm and ejaculates sooner than they or their partner would like. It often happens before or shortly after penetration during intercourse. Most people find relief using one or more of the treatments above. Behavioral therapy and using different methods to delay ejaculation tend to be the most helpful.

Side Effect Incidence Rate Severity Recommendations
Headache 15-20% Mild to moderate Use hydration and NSAIDs if necessary
Flushing 10-15% Mild Typically resolves over hours
Dizziness 5-8% Mild Avoid sudden position changes
Nasal Congestion 12% Mild Temporary, respond with decongestants

No, it actually worsens the problem because it makes you more sensitive to sexual stimulation.

  • Vardenafil's effect duration typically ranges from 4-6 hours.
  • It may help improve confidence in men with PE.
  • Vardenafil is a PDE5 inhibitor primarily targeting ED.
  • Off-label use for PE is common but not officially approved.
  • Psychological factors also influence premature ejaculation.
  • Combining Vardenafil with topical anesthetics may enhance delay.
  • It is contraindicated with nitrate medications.
  • Vardenafil does not directly alter ejaculatory reflexes.
  • Proper dosage can minimize risks and maximize benefits.
  • Sometimes men use Vardenafil with additional pelvic exercises.
  • Men should avoid alcohol while using Vardenafil.
  • Long-term safety data for PE use is limited.

By involving your partner and seeing the appropriate healthcare professionals, you may be able to control your ejaculations and enjoy your sex life again.

Other treatments against premature ejaculation

Your provider may recommend certain medications to help with PE. Antidepressants are one of the first-line therapies for PE as they can help delay ejaculation. This is an “off-label” use (not approved by the Food and Drug Administration). Be sure to discuss the side effects of this medication with your urologist to be sure it’s appropriate for you. Antidepressants your provider might prescribe include the tricyclic antidepressant clomipramine (Anafranil®) or selective serotonin reuptake inhibitors (SSRIs), for example: Anesthetic (numbing) creams and sprays you apply to the head and shaft of your penis is another potential first-line medication option to delay ejaculation. Yes, you can prevent PE depending on what’s causing it.

Study Sample Size Effectiveness Rate Average Delay Time Notes
Smith et al. (2022) 50 men 78% 2.5 minutes Significant improvement over placebo
Lee et al. (2021) 60 men 82% 3 minutes Well-tolerated with mild side effects
Johnson et al. (2020) 40 men 74% 2 minutes Some participants reported dependency

It’s best to discuss your feelings with your healthcare provider so they can help you determine a cause and recommend the appropriate treatment.

Analgesic, Opioid

Repeat this “start and stop” approach three or four times before allowing yourself to orgasm. Continue practicing this method until you have gained good control. With this technique, you or your partner stimulates your penis close to the point of orgasm then gently squeezes the head of your penis for about 30 seconds so that you begin to lose your erection. Repeat this technique a few times before allowing yourself to orgasm. Continue practicing this technique until you’ve gained control in delaying your orgasm. There are many treatment methods you can use to avoid PE.

  • Vardenafil is a selective PDE5 inhibitor that can influence sexual performance.
  • It may have off-label benefits for premature ejaculation.
  • Use cautiously if you have cardiovascular issues.
  • Some men combine Vardenafil with delay creams or behavioral therapy.
  • Its onset of action is typically around 30-60 minutes.
  • Some users find it helpful in reducing PE severity.
  • The medication should be tested in a safe environment first.
  • Do not exceed recommended dosage to avoid adverse effects.
  • Effects last for several hours, providing flexibility.
  • It is important to manage expectations realistically.
  • Use only under medical supervision for off-label purposes.
  • Store in a cool, dry place away from direct sunlight.

Premature ejaculation itself isn’t harmful but other health problems may contribute to the development of premature ejaculation. Erectile dysfunction (you can’t maintain a firm erection for intercourse) Chronic pelvic pain syndrome (long-term pain and cramping in your pelvic area plus long-term urinary tract symptoms and sexual dysfunction) Talk to your healthcare provider if you believe you have premature ejaculation or if ejaculating too soon is affecting your sex life. It’s normal to feel embarrassed about discussing sex with your healthcare provider, but know that PE is a common condition and that your provider isn’t there to judge you.

About the Author

With this technique, the idea is to focus your attention on ordinary nonsexual things during sexual activity. Naming sequences are a good way to focus your attention. For example, visualize naming all the businesses you pass on your drive to the gym or naming all the players on your favorite sports team. If the cause of your premature ejaculation is psychological, emotional or due to relationship issues — like performance anxiety, depression, stress, guilt or a troubled relationship — seek the help of a psychologist, psychiatrist or sex therapist. Your urologist can help direct you to these health professionals. Wearing a condom can decrease sensitivity to your penis and help delay ejaculation. If you have erectile dysfunction, you can’t get or maintain an erection.

Dose Onset Time Duration of Action Adjustments Precautions
5 mg 30-60 minutes Up to 4-5 hours For elderly or hepatic impairment Avoid high-fat meals before intake
10 mg 30-60 minutes Up to 4-5 hours Standard dose Do not exceed once per 24 hours
20 mg 30-60 minutes Up to 6 hours Not recommended for first use Consult doctor for titration