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Also, there was no limitation to the intervention form
Why Sex Drive Might Change With Menopause
The publication bias was checked using the funnel plot and Begg’s and Egger’s methods (Table 3 and Figure 5). The results of both Begg’s (z = 0.55, P = 0.583) and Egger’s tests showed the absence of the publication bias (t = 0.187, P = 0.089), but the slope of the line was significant (t = 24.96, P = 0.000). Most of the articles included in the present study reported positive effects on the sexual function of women of reproductive age. Also, most studies investigated the side effects of herbal medicines and reported that the side effects were insignificant or there were no side effects. However, this evidence is not conclusive, and more research is required.
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In addition, few studies have investigated the effects of herbal medicines on sexual function and satisfaction among women of reproductive age, most of which have been conducted in Iran. Thus, it is crucial to do more research with wider and various sample sizes in different regions of the world. The majority of studies were conducted on Russian olive (4 studies), followed by bindii, ginseng, and vitagnus, each with two studies. The findings of the studies conducted on Russian olive showed that it improved some dimensions of sexual function, including desire, arousal, satisfaction, and orgasm in women. Russian olive, vitagnus, palm pollen (13), fenugreek, pomegranate peel (15), etc., are among plants with phytoestrogen properties.
Ospemifene (Osphena)
Phytoestrogens are compounds with estrogenic properties found in plants with estrogenic and anti-estrogenic properties. The exact mechanism of the effect of these compounds is not still known, but it seems that phytoestrogens affect the hypothalamus-pituitary axis. As a result, they lead to decreased secretion of follicle-stimulating hormone (FSH) and prolactin, regulated secretion of luteinizing hormone (LH), and increased sex hormones, such as estrogen and androgen, resulting in increased sexual desire, arousal, efficiency, and orgasm (13). Sha'ari et al.’s (2021) systematic review of the beneficial consequence of natural products on FSD showed that Korean ginseng and bindii significantly and positively affected improving female sexual function. In contrast, other natural products did not improve FSD significantly compared to the placebo (33). used in the selected articles, including oral, inhaled, topical, etc.
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In this research, all clinical trials
Lifestyle and home remedies
The levels of free (P = 0.046) and bioavailable (P < 0.048) testosterone increased in women who received bindii (18). Akhtari et al.’s (2014) study revealed that the patients of the bindii group had a significant improvement in the total scores of sexual function (P < 0.001) and the dimensions of desire (P < 0.001), arousal (P < 0.037), moisture (P < 0.001), satisfaction (P < 0.001), and pain (P < 0.041) at the end of the fourth week (29). (2015) found a considerable rise in free testosterone (P = 0.043), estradiol (P = 0.013), and desire and arousal (P = 0.026) in the intervening group. Also, the intervention group reported a significantly higher frequency of intercourse compared to the placebo (P = 0.013) after two months of intervention. According to their results, fenugreek extract may be a therapeutic item to increase women’s arousal and desire (19).
3. Data Sources
(2017) compared two intervention and control groups four weeks after the start of the intervention and found a significant difference between their excitement and sexual desire (P < 0.05). However, two months after administrating saffron and placebo, both groups were significantly different in their total scores of sexual function and all its dimensions except moisture (P < 0.05). It was, therefore, concluded that Saffron could improve sexual function and its dimensions in women (20). The findings of Motaharinezhad et al.’s (2021) study showed that the rose oil group significantly improved female sexual function (P < 0.001) two months after the intervention (26.5 ± 7.13) compared to before the intervention (20.90 ± 3.34) and the control group (P = 0.320). The mean scores of sexual function in the two groups were statistically significant (P < 0.001) (21).
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(2022) reported that the total score of sexual function significantly increased from 21.06 ± 2.58 to 27.31 ± 2.59 in the intervention group (P < 0.0001). Sexual arousal, orgasm, moisture, dyspareunia, and satisfaction also increased considerably in the intervention group (P < 0.0001) (22). In Hessami et al.’s (2021) study, the improvement in the total score of sexual function was significantly elevated in the celery seed group than in the placebo group at the final week of six weeks of intervention (P < 0.001). The increased total score of sexual function was mainly due to the improvement of sexual urge or desire (P < 0.001), arousal (P < 0.001), moisture (P < 0.001), and painful sex (P = 0.033) at the end of the study (24). (2020) showed that the total scores of sexual function and its dimensions changed significantly in both intervention and control groups. used the FSFI, a valid and reliable
Further Enhancement of Women’s Libido
However, ginseng and vitamin E supplements (100 units of vitamin E, 67 mg of Korean ginseng, and 40 mg of Siberian ginseng) only improved the domains of desire (P = 0.030) and sexual satisfaction (P = 0.028) (25). In Chung et al.’s (2015) study, the total score of sexual function increased after treatment with Korean red ginseng (from 20.13 ± 2.87 to 23.98 ± 4.10, P = 0.015) and placebo (from 20.06 ± 2.64 to 23.78 ± 3.28, P = 0.003). However, this interchange has not been considered significantly between the two groups (P = 0.702). Medication with Korean red ginseng also improved the dimensions of desire, arousal, orgasm, and satisfaction significantly, while there were no therapeutic effects compared to the placebo (28). (2015) showed that treatment with winter cherry root extracts significantly improved the total score of sexual function (P < 0.001) and the scores of arousal (P < 0.001), moisture (P < 0.001), orgasm (P = 0.004), satisfaction (P < 0.001), the Female Sexual Distress Scale (FSDS) (P < 0.001) and the number of successful intercourse (P < 0.001) (26).
A Note on Gender and Sex Terminology
(2018) reported a statistically significant increase in desire (P < 0.001), arousal (P < 0.001), moisture (P < 0.005), orgasm (P < 0.001), satisfaction (P < 0.001), pain (P < 0.002), and the total score of sexual function (P < 0.001) in the intervention than in the placebo group (27). In Mohammadzadeh et al.’s (2019) study, there was a statistically significant improvement in the mean scores of the orgasm and sexual satisfaction dimensions in the intervening group than in the placebo group after four and eight weeks (P < 0.001) (30). (2018), squill bulb oil could significantly improve female sexual function in dimensions of desire, moisture, orgasm, and arousal compared to the placebo after one month of administration. The findings of 12 studies were combined in a meta-analysis. Considering that the I-SQUARED statistic was > 50% (85.6%) in the total score of sexual function, and given the data heterogeneity, the random effect was used instead of the fixed effect to integrate the data.
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According to the meta-analysis results, the difference in the mean scores of the two groups was 0.95 at a confidence level of 95% (CI: 0.803 - 1.097), which was significant (z = 12.64, P = 0.001) and revealed an improvement in the total score of female sexual function in the intervention group (Figure 2). The publication bias was checked using the funnel plot and Begg’s and Egger’s methods (Table 2 and Figure 3). The results of both Begg’s (z = 0.14, P = 0.891) and Egger’s tests showed the absence of the publication bias (t = 0.17, P = 0.867), but the slope of the line was significant (t = 7.25, P = 0.000). Considering that the I-SQUARED statistic was > 50% (83.2%) in the case of sexual satisfaction, and given the data heterogeneity, the erection tablets random effect was used instead of the fixed effect to integrate the data. According to the meta-analysis results, the difference in the mean score of the two groups was 0.84 at a confidence level of 95% (CI: 0.476 - 1.21), which was significant (z = 4.5, P = 0.001) and revealed an improvement in the total score of female sexual satisfaction in the intervention group (Figure 4). tool; however, some studies did not
- Research on effectiveness of female sex tablets is often limited.
- Psychological factors significantly influence sexual response.
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clearly explain the randomization and blinding methods. It is suggested to conduct future clinical trials with a better design.
- Some women report increased confidence after using sex tablets.
- Expect different results depending on individual physiology.
- Make sure to purchase from reputable sources to ensure quality.
- Keep track of side effects or adverse reactions for medical consultation.
- Combining diet, exercise, and supplements can optimize results.
- Managing stress and emotional health can improve satisfaction.
- Look for products with transparent ingredient lists.
- Stay informed about new developments in female sexual health products.
It seems that herbal medicines positively
- Female sex tablets are sometimes used to intensify orgasms.
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- Effectiveness of sex tablets varies depending on individual physiology.
- It's important to follow dosage instructions to avoid adverse effects.
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affect sexual function and satisfaction of women
- Supplements are sometimes used with other sexual health aids.
- Regular exercise can complement the effects of sex tablets.
- Adequate hydration is important when using these products.
- Be aware of potential interactions with other medications.
- Female libido can be affected by hormonal changes, which tablets may help address.
- Use these products as part of a consensual and open sexual relationship.
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of reproductive age and can be an effective and safe treatment for FSD.
Do They Work?
This study only included English-language articles, whose samples were all women ≥ 18 years. However, none of the two aforementioned articles reported a significant positive effect of ginseng on the sexual function score of women in the intervention compared to the placebo group. A systematic review by Martimbianco et al. (2020), designed to assess the consequence of bindii on FSD, indicated a significant increase in sexual function scores in premenopausal and postmenopausal women treated with this herb (34). The findings of this study were consistent with the results of the current research.
More FAQ
Jurado et al.’s (2020) systematic review to study the effects of natural products on sexual dysfunction in women of all age groups concluded that despite the low quality of many studies, the large amount of herbal product interventions seemed to upgrade sexual dysfunction, particularly hyposexuality disorders, including the primary and medicine-induced types (35). However, our study examined only women of reproductive age with primary sexual dysfunction. One limitation of this study was the selection of articles only in English and Persian, which led to excluding non-English or non-Persian articles. In addition, most studies were conducted in Iran, making it difficult to generalize the data to other countries. Among the strengths of the present study was the search in databases by two independent authors and the use of manual in addition to electronic search, which resulted in the retrieval of more articles.